Metoclopramide Impurity 104 DiHCl CAS 41489-50-3 (free base)
| CAS No. | 41489-50-3 (free base) |
| Molecular Formula | C29H42Cl2N6O5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Metoclopramide Impurity 104 DiHCl.
As a process- or degradation-related impurity, Metoclopramide Impurity 104 DiHCl (CAS 41489-50-3 (free base), C29H42Cl2N6O5HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Metoclopramide Impurity 104 DiHCl (C29H42Cl2N6O5HCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Metoclopramide Impurity 104 DiHCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C29H42Cl2N6O5 2*HCl |
| Molecular Weight | 662.05 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Metoclopramide Standards
- Metoclopramide EP Impurity E (CAS 100-36-7)
- Metoclopramide Impurity 68 (CAS 101385-94-8)
- Metoclopramide impurity 70 (CAS 102313-35-9)
- Metoclopramide Impurity 11 (CAS 111049-74-2)
- Metoclopramide-related Impurity (CAS 121048-67-7)
- Metoclopramide-d3 (CAS 1216522-89-2)
- Metoclopramide impurity 60 (CAS 1242047-97-7)
- Metoclopramide Impurity 83 (CAS 1242047-99-9)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com